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Alnylam Pharmaceuticals

ALNY · Updated 11/13/2026

Revenue

$3.7B

Fiscal 2025

Net income

(18.3M)

Fiscal 2025

Free cash flow

$465.4M

Fiscal 2025

Net cash / (debt)

—

Fiscal 2025

Five-year financials

Fiscal year20252024202320222021
Revenue$3.7B$2.2B$1.8B$1.0B$844.3M
Net income(18.3M)(278.2M)(440.2M)(1.1B)(852.8M)
Diluted EPS—————
Operating cash flow$524.1M(8.3M)$104.2M(541.3M)(641.7M)
Free cash flow$465.4M(42.6M)$41.9M(613.3M)(718.1M)
Cash$1.7B$966.4M$812.7M$866.4M$820.0M
Total debt—————

Financial trends

Historical · FY2021–FY2025

Source: Reported annual filings (10-K / 20-F) and provider data. Fiscal years as reported; margins are calculated from the reported figures shown.

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Where the cash went

Cumulative, fiscal 2021–2025, straight from the reported cash-flow statements.

Reinvested in capex

—

of operating cash flow

Returned to owners

—

of free cash flow (buybacks + dividends)

Diluted share count

—

change 2021–2025

Capital expenditure $303.6MBar width = share of $303.6M (spending exceeded operating cash flow)
Operating cash flow($563.0M)
Capital expenditure($303.6M)
Free cash flow($866.7M)
Share buybacks—
Dividends paid—
Acquisitions (net)—
Net debt issued / (repaid)—
Stock-based compensation (non-cash)—

"—" means a year didn't report that line, so no total is shown rather than an estimate.

Alnylam Pharmaceuticals return on capital (fiscal 2025)

ROIC

28.4%

Return on capital

32.6%

Return on equity

73.3%

Return on assets

6.8%

Gross margin

81.6%

Operating margin

13.5%

Net debt / EBITDA

-1.17x

Alnylam Pharmaceuticals insider buying and selling

Recent open-market trades reported on Form 4. Context only — not a reason to buy or sell.

DateInsiderTypeSharesPrice
2026-10-02SUPRAN BRYANSale1,758$226.88
2026-06-01PYOTT DAVID E ISale1,222$299.87
2026-06-01PYOTT DAVID E ISale1,175$298.91
2026-06-01PYOTT DAVID E ISale921$297.71
2026-06-01PYOTT DAVID E ISale495$300.72
2026-06-01PYOTT DAVID E ISale17$302.65

SEC filings

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